Pseudomonas aeruginosa M18, PAM18_4547

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_4547
Name
Replicon chromosome
Genomic location 5027714 - 5028523 (- strand)

Cross-References

RefSeq YP_005977130.1
GI 386060608
Entrez 12568615
NCBI Locus Tag PAM18_4547

Product

Feature Type CDS
Coding Frame 1
Product Name
putative ATP-binding component of ABC transporter
Synonyms
Evidence for Translation
Charge (pH 7) -0.07
Kyte-Doolittle Hydrophobicity Value 0.018
Molecular Weight (kDa) 29.6
Isoelectric Point (pI) 6.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7CHA MEMBRANE PROTEIN 07/05/20 Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pseudomonas aeruginosa PAO1 3.9 ELECTRON MICROSCOPY 100.0
7CH9 MEMBRANE PROTEIN 07/05/20 Cryo-EM structure of P.aeruginosa MlaFEBD Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.5 ELECTRON MICROSCOPY 100.0
7CH8 MEMBRANE PROTEIN 07/05/20 Cryo-EM structure of P.aeruginosa MlaFEBD with ADP-V Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.9 ELECTRON MICROSCOPY 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004045 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_4547

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 8.7e-19
Percent Identity: 30.4
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 8.7e-19
Percent Identity: 30.4
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 8.7e-19
Percent Identity: 30.4

References

No references are associated with this feature.