Pseudomonas aeruginosa M18, PAM18_4691 (oprJ)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_4691
|
| Name |
oprJ
|
| Replicon | chromosome |
| Genomic location | 5190783 - 5192231 (- strand) |
Cross-References
| RefSeq | YP_005977273.1 |
| GI | 386060751 |
| Entrez | 12568764 |
| NCBI Locus Tag | PAM18_4691 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
Multidrug efflux outer membrane protein OprJ
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 3.71 |
| Kyte-Doolittle Hydrophobicity Value | -0.256 |
| Molecular Weight (kDa) | 52299.1 |
| Isoelectric Point (pI) | 9.14 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| OprJ | OprJ is the outer membrane channel component of the MexCD-OprJ multidrug efflux complex. [PMID:9449262] | ARO:3000802 | protein homolog model | Strict | 880.9 | 99.37 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 5AZS | MEMBRANE PROTEIN | 10/21/15 | Crystal structure of a membrane protein from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) | 3.1 | X-RAY DIFFRACTION | 99.8 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 293 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004255 (330 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_4691
Search term: oprJ
Search term: Multidrug efflux outer membrane protein OprJ
|
Human Homologs
References
No references are associated with this feature.