Pseudomonas aeruginosa M18, PAM18_4769

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_4769
Name
Replicon chromosome
Genomic location 5280069 - 5280653 (+ strand)

Cross-References

RefSeq YP_005977351.1
GI 386060829
Entrez 12568843
NCBI Locus Tag PAM18_4769

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidyl-tRNA hydrolase
Synonyms
Evidence for Translation
Charge (pH 7) 5.39
Kyte-Doolittle Hydrophobicity Value -0.114
Molecular Weight (kDa) 20.8
Isoelectric Point (pI) 9.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4DHW HYDROLASE 01/30/12 Crystal structure of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with Adipic acid at 2.4 Angstrom resolution Pseudomonas aeruginosa 2.43 X-RAY DIFFRACTION 100.0
4JC4 HYDROLASE 02/21/13 Crystal structure of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa at 2.25 angstrom resolution Pseudomonas aeruginosa 2.25 X-RAY DIFFRACTION 100.0
4QBK HYDROLASE 05/08/14 Crystal structure of the complex of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with amino acyl-tRNA analogue at 1.77 Angstrom resolution Pseudomonas aeruginosa 1.77 X-RAY DIFFRACTION 100.0
4FYJ HYDROLASE 07/04/12 Crystal Structure of P. aeruginosa peptidyl-tRNA hydrolase Pseudomonas aeruginosa 1.77 X-RAY DIFFRACTION 100.0
4QD3 HYDROLASE 05/13/14 Crystal structure of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with 5-azacytidine at 1.89 Angstrom resolution Pseudomonas aeruginosa 1.89 X-RAY DIFFRACTION 100.0
4DJJ HYDROLASE 02/02/12 Crystal structure of the complex of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with Pimelic acid at 2.9 Angstrom resolution Pseudomonas aeruginosa 2.94 X-RAY DIFFRACTION 100.0
4QAJ HYDROLASE 05/05/14 Crystal structure of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa at 1.5 Angstrom resolution Pseudomonas aeruginosa 1.5 X-RAY DIFFRACTION 100.0
4ERX HYDROLASE 04/21/12 Crystal structure of the complex of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with diethylene glycol at 2.5 Angstrom resolution Pseudomonas aeruginosa 2.5 X-RAY DIFFRACTION 100.0
4FNO HYDROLASE 06/20/12 Crystal structure of peptidyl t-RNA hydrolase from Pseudomonas aeruginosa at 2.2 Angstrom resolution Pseudomonas aeruginosa 2.25 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004322 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_4769

Human Homologs

References

No references are associated with this feature.