Pseudomonas aeruginosa M18, PAM18_4959 (accC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_4959
|
| Name |
accC
|
| Replicon | chromosome |
| Genomic location | 5494181 - 5495530 (+ strand) |
Cross-References
| RefSeq | YP_005977541.1 |
| GI | 386061019 |
| Entrez | 12569043 |
| NCBI Locus Tag | PAM18_4959 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
acetyl-CoA carboxylase biotin carboxylase subunit
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -5.82 |
| Kyte-Doolittle Hydrophobicity Value | -0.183 |
| Molecular Weight (kDa) | 48.9 |
| Isoelectric Point (pI) | 6.28 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 2VQD | LIGASE | 03/13/08 | Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP | PSEUDOMONAS AERUGINOSA | 2.41 | X-RAY DIFFRACTION | 100.0 |
| 2C00 | LIGASE | 03/21/08 | Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form | PSEUDOMONAS AERUGINOSA | 2.5 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 630 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004477 (535 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_4959
Search term: accC
Search term: acetyl-CoA carboxylase biotin carboxylase subunit
|
Human Homologs
|
Ensembl
110, assembly
GRCh38.p14
|
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value:
5.0e-120
Percent Identity:
47.5
|
|
Ensembl
110, assembly
GRCh38.p14
|
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value:
5.0e-120
Percent Identity:
47.5
|
|
Ensembl
110, assembly
GRCh38.p14
|
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value:
5.0e-120
Percent Identity:
47.5
|
References
No references are associated with this feature.