Pseudomonas aeruginosa M18, PAM18_5062 (orn)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_5062
Name
orn
Replicon chromosome
Genomic location 5607409 - 5607951 (- strand)

Cross-References

RefSeq YP_005977644.1
GI 386061122
Entrez 12569150
NCBI Locus Tag PAM18_5062

Product

Feature Type CDS
Coding Frame 1
Product Name
oligoribonuclease
Synonyms
Evidence for Translation
Charge (pH 7) -5.38
Kyte-Doolittle Hydrophobicity Value -0.494
Molecular Weight (kDa) 20.8
Isoelectric Point (pI) 5.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7VA2 HYDROLASE 08/27/21 PaOrn Oligoribonuclease D11A mutant with product GMP complex structure Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.3 X-RAY DIFFRACTION 99.4
7VA3 HYDROLASE 08/27/21 PaOrn Oligoribonuclease D11A mutant with substrate pGpG complex structure Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT 1.8 X-RAY DIFFRACTION 99.4
7V9Z HYDROLASE 08/27/21 PaOrn Oligoribonuclease native structure Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.85 X-RAY DIFFRACTION 100.0
7VA6 HYDROLASE 08/27/21 PaOrn Oligoribonuclease D11A mutant with RNA GU complex structure Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT 2.1 X-RAY DIFFRACTION 99.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 216 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004566 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_5062
Search term: orn
Search term: oligoribonuclease

Human Homologs

Ensembl 110, assembly GRCh38.p14
RNA exonuclease 2 [Source:HGNC Symbol;Acc:HGNC:17851]
E-value: 3.9e-47
Percent Identity: 50.6

References

No references are associated with this feature.