Pseudomonas aeruginosa M18, PAM18_5605

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_5605
Name
Replicon chromosome
Genomic location 6229539 - 6231326 (+ strand)

Cross-References

RefSeq YP_005978184.1
GI 386061662
Entrez 12569704
NCBI Locus Tag PAM18_5605

Product

Feature Type CDS
Coding Frame 1
Product Name
putative two-component sensor
Synonyms
Evidence for Translation
Charge (pH 7) -11.89
Kyte-Doolittle Hydrophobicity Value -0.084
Molecular Weight (kDa) 66.0
Isoelectric Point (pI) 5.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3N24 TRANSFERASE 05/17/10 The crystal structure of a two-component sensor domain (3rd form) from Pseudomonas aeruginosa PA01 Pseudomonas aeruginosa 2.056 X-RAY DIFFRACTION 100.0
4LLC TRANSFERASE 07/09/13 The crystal structure of R60E mutant of the histidine kinase (KinB) sensor domain from Pseudomonas aeruginosa PA01 Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 99.2
3L34 TRANSFERASE 12/16/09 The crystal structure of a two-component sensor domain (2nd form) from Pseudomonas aeruginosa PA01 Pseudomonas aeruginosa 1.7 X-RAY DIFFRACTION 100.0
4LLE TRANSFERASE 07/09/13 The crystal structure of R60L mutant of the histidine kinase (KinB) sensor domain from Pseudomonas aeruginosa PA01 Pseudomonas aeruginosa 1.68 X-RAY DIFFRACTION 99.2
3KKB TRANSFERASE 11/05/09 The crystal structure of a two-component sensor domain from Pseudomonas aeruginosa PA01 Pseudomonas aeruginosa PAO1 1.881 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005024 (530 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_5605

Human Homologs

References

No references are associated with this feature.