Pseudomonas aeruginosa DK2, PADK2_01490
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa DK2
GCF_000271365.1|latest |
| Locus Tag |
PADK2_01490
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 331654 - 332754 (+ strand) |
Cross-References
| RefSeq | YP_006480295.1 |
| GI | 392981708 |
| Entrez | 13171756 |
| NCBI Locus Tag | PADK2_01490 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
polyamine transport protein
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 1.14 |
| Kyte-Doolittle Hydrophobicity Value | -0.298 |
| Molecular Weight (kDa) | 40.5 |
| Isoelectric Point (pI) | 7.59 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 3TTK | TRANSPORT PROTEIN | 09/14/11 | Crystal structure of apo-SpuD | Pseudomonas aeruginosa | 2.97 | X-RAY DIFFRACTION | 99.7 |
| 3TTM | TRANSPORT PROTEIN | 09/15/11 | Crystal structure of SpuD in complex with putrescine | Pseudomonas aeruginosa | 2 | X-RAY DIFFRACTION | 99.7 |
Drugs Targeting this Protein
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
| Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
| Spermidine | DB03566 | DrugBank | 5.1.4 | P0AFK9 | Spermidine/putrescine-binding periplasmic protein | 36.5 | 367 | 8.0e-60 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 306 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000297 (535 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PADK2_01490
Search term: polyamine transport protein
|
Human Homologs
References
No references are associated with this feature.