Strain |
Pseudomonas aeruginosa DK2
GCF_000271365.1|latest |
Locus Tag |
PADK2_02155
|
Name |
|
Replicon | chromosome |
Genomic location | 470158 - 471615 (+ strand) |
RefSeq | YP_006480426.1 |
GI | 392981839 |
Entrez | 13171967 |
NCBI Locus Tag | PADK2_02155 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -2.79 |
Kyte-Doolittle Hydrophobicity Value | -0.216 |
Molecular Weight (kDa) | 52.6 |
Isoelectric Point (pI) | 5.32 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
OprM | OprM is an outer membrane factor protein found in Pseudomonas aeruginosa and Burkholderia vietnamiensis. It is part of the MexAB-OprM, MexVW-OprM, MexXY-OprM and the AmrAB-OprM complex. [PMID:16508113, PMID:16511029, PMID:15797729] | ARO:3000379 | protein homolog model | Strict | 915.6 | 99.79 | 3.2.5 |
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7AKZ | TRANSLOCASE | 10/02/20 | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 3.2 | X-RAY DIFFRACTION | 99.7 |
4Y1K | MEMBRANE PROTEIN | 02/07/15 | PALMITOYLATED OPRM OUTER MEMBRANE FACTOR | Pseudomonas aeruginosa | 3.8 | X-RAY DIFFRACTION | 99.7 |
1WP1 | MEMBRANE PROTEIN | 08/28/04 | Crystal structure of the drug-discharge outer membrane protein, OprM | Pseudomonas aeruginosa | 2.56 | X-RAY DIFFRACTION | 99.7 |
6ZRE | TRANSLOCASE | 07/13/20 | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 2.8 | X-RAY DIFFRACTION | 99.7 |
6TA6 | ANTIMICROBIAL PROTEIN | 10/29/19 | MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs | Pseudomonas aeruginosa | 3.2 | ELECTRON MICROSCOPY | 99.7 |
6IOL | MEMBRANE PROTEIN | 10/30/18 | Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state) | Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1 | 3.76 | ELECTRON MICROSCOPY | 99.7 |
6IOK | MEMBRANE PROTEIN | 10/30/18 | Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) | Pseudomonas aeruginosa PAO1 | 3.64 | ELECTRON MICROSCOPY | 99.7 |
6TA5 | ANTIMICROBIAL PROTEIN | 10/29/19 | OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs | Pseudomonas aeruginosa | 3.2 | ELECTRON MICROSCOPY | 99.7 |
3D5K | MEMBRANE PROTEIN | 05/16/08 | Crystal structure of the OprM channel in a non-symmetrical space group | Pseudomonas aeruginosa | 2.4 | X-RAY DIFFRACTION | 99.7 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 316 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000418 (534 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PADK2_02155
|