Pseudomonas aeruginosa DK2, PADK2_08495

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_08495
Name
Replicon chromosome
Genomic location 1831901 - 1834666 (+ strand)

Cross-References

RefSeq YP_006481694.1
GI 392983107
Entrez 13173809
NCBI Locus Tag PADK2_08495

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA gyrase subunit A
Synonyms
Evidence for Translation
Charge (pH 7) -38.07
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 100.9
Isoelectric Point (pI) 4.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones Point mutation of Pseudomonas aeruginosa gyrA resulted in the lowered affinity between fluoroquinolones and gyrA. Thus, conferring resistance. [PMID:22821356, PMID:8540700] ARO:3003684 protein variant model D87N Strict 1743.8 99.67 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 631 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002447 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_08495

Human Homologs

References

No references are associated with this feature.