Pseudomonas aeruginosa DK2, PADK2_10805 (pheS)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa DK2
GCF_000271365.1|latest |
| Locus Tag |
PADK2_10805
|
| Name |
pheS
|
| Replicon | chromosome |
| Genomic location | 2291907 - 2292923 (+ strand) |
Cross-References
| RefSeq | YP_006482150.1 |
| GI | 392983563 |
| EC Number | 6.1.1.20 |
| Entrez | 13174359 |
| NCBI Locus Tag | PADK2_10805 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
phenylalanyl-tRNA synthetase subunit alpha
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -7.58 |
| Kyte-Doolittle Hydrophobicity Value | -0.248 |
| Molecular Weight (kDa) | 38.0 |
| Isoelectric Point (pI) | 5.79 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 4P72 | LIGASE/LIGASE INHIBITOR | 03/25/14 | PheRS in complex with compound 2a | Pseudomonas aeruginosa | 2.62 | X-RAY DIFFRACTION | 99.7 |
| 4P74 | LIGASE/LIGASE INHIBITOR | 03/25/14 | PheRS in complex with compound 3a | Pseudomonas aeruginosa | 2.7 | X-RAY DIFFRACTION | 99.7 |
| 4P73 | LIGASE/LIGASE Inhibitor | 03/25/14 | PheRS in complex with compound 1a | Pseudomonas aeruginosa | 3.03 | X-RAY DIFFRACTION | 99.7 |
| 4P75 | LIGASE/LIGASE INHIBITOR | 03/25/14 | PheRS in complex with compound 4a | Pseudomonas aeruginosa | 2.96 | X-RAY DIFFRACTION | 99.7 |
| 4P71 | LIGASE | 03/25/14 | Apo PheRS from P. aeuriginosa | Pseudomonas aeruginosa | 2.79 | X-RAY DIFFRACTION | 99.7 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 666 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002831 (535 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PADK2_10805
Search term: pheS
Search term: phenylalanyl-tRNA synthetase subunit alpha
|
Human Homologs
References
No references are associated with this feature.