Pseudomonas aeruginosa DK2, PADK2_15590

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_15590
Name
Replicon chromosome
Genomic location 3376534 - 3378501 (+ strand)

Cross-References

RefSeq YP_006483099.1
GI 392984512
Entrez 13172113
NCBI Locus Tag PADK2_15590

Product

Feature Type CDS
Coding Frame 1
Product Name
3-methylcrotonoyl-CoA carboxylase subunit alpha
Synonyms
Evidence for Translation
Charge (pH 7) -16.86
Kyte-Doolittle Hydrophobicity Value -0.218
Molecular Weight (kDa) 71.1
Isoelectric Point (pI) 5.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3U9S LIGASE 10/19/11 Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, CoA complex Pseudomonas aeruginosa 3.5 X-RAY DIFFRACTION 94.5
3U9T LIGASE 10/19/11 Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme Pseudomonas aeruginosa 2.9 X-RAY DIFFRACTION 94.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 643 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003427 (523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_15590

Human Homologs

Ensembl 110, assembly GRCh38.p14
methylcrotonyl-CoA carboxylase subunit 1 [Source:HGNC Symbol;Acc:HGNC:6936]
E-value: 2.9e-156
Percent Identity: 46.5

References

No references are associated with this feature.