Pseudomonas aeruginosa DK2, PADK2_20760
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa DK2
GCF_000271365.1|latest |
| Locus Tag |
PADK2_20760
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 4468558 - 4470111 (- strand) |
Cross-References
| RefSeq | YP_006484123.1 |
| GI | 392985536 |
| Entrez | 13175063 |
| NCBI Locus Tag | PADK2_20760 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
coenzyme A ligase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -6.98 |
| Kyte-Doolittle Hydrophobicity Value | -0.068 |
| Molecular Weight (kDa) | 56.6 |
| Isoelectric Point (pI) | 6.15 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 5OE4 | LIGASE | 07/07/17 | Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 2) | Pseudomonas aeruginosa PAO1 | 1.904 | X-RAY DIFFRACTION | 100.0 |
| 5OE3 | LIGASE | 07/07/17 | Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 1) | Pseudomonas aeruginosa PAO1 | 1.43 | X-RAY DIFFRACTION | 100.0 |
| 5OE5 | LIGASE | 07/07/17 | Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 3) | Pseudomonas aeruginosa PAO1 | 1.74 | X-RAY DIFFRACTION | 100.0 |
| 5OE6 | LIGASE | 07/07/17 | Crystal structure of the N-terminal domain of PqsA in complex with 6-fluoroanthraniloyl-AMP (crystal form 1) | Pseudomonas aeruginosa PAO1 | 1.67 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 600 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000959 (296 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PADK2_20760
Search term: coenzyme A ligase
|
Human Homologs
|
Ensembl
110, assembly
GRCh38.p14
|
acyl-CoA synthetase short chain family member 1 [Source:HGNC Symbol;Acc:HGNC:16091]
E-value:
1.6e-24
Percent Identity:
24.3
|
|
Ensembl
110, assembly
GRCh38.p14
|
acyl-CoA synthetase short chain family member 1 [Source:HGNC Symbol;Acc:HGNC:16091]
E-value:
1.6e-24
Percent Identity:
24.3
|
References
No references are associated with this feature.