Pseudomonas aeruginosa DK2, PADK2_22915
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa DK2
GCF_000271365.1|latest |
| Locus Tag |
PADK2_22915
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 4935866 - 4936777 (+ strand) |
Cross-References
| RefSeq | YP_006484548.1 |
| GI | 392985961 |
| EC Number | 1.1.1.169 |
| Entrez | 13173260 |
| NCBI Locus Tag | PADK2_22915 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
2-dehydropantoate 2-reductase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 6.46 |
| Kyte-Doolittle Hydrophobicity Value | -0.214 |
| Molecular Weight (kDa) | 33.0 |
| Isoelectric Point (pI) | 8.60 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 5ZIK | OXIDOREDUCTASE | 03/16/18 | Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 2.45 | X-RAY DIFFRACTION | 99.7 |
| 6K1R | OXIDOREDUCTASE | 05/12/19 | Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa in complex with NAD+ and ketopantoate | Pseudomonas aeruginosa PAO1 | 2.55 | X-RAY DIFFRACTION | 99.7 |
| 5ZIX | OXIDOREDUCTASE | 03/17/18 | Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa bound to NADP+ | Pseudomonas aeruginosa PAO1 | 2.57 | X-RAY DIFFRACTION | 99.7 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 289 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG003987 (534 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PADK2_22915
Search term: 2-dehydropantoate 2-reductase
|
Human Homologs
References
No references are associated with this feature.