Pseudomonas aeruginosa DK2, PADK2_25445

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_25445
Name
Replicon chromosome
Genomic location 5482477 - 5482959 (+ strand)

Cross-References

RefSeq YP_006485054.1
GI 392986467
Entrez 13170458
NCBI Locus Tag PADK2_25445

Product

Feature Type CDS
Coding Frame 1
Product Name
acetyltransferase, GNAT family protein
Synonyms
Evidence for Translation
Charge (pH 7) 0.86
Kyte-Doolittle Hydrophobicity Value -0.137
Molecular Weight (kDa) 17.8
Isoelectric Point (pI) 7.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4KUB TRANSFERASE 05/21/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with CoA Pseudomonas aeruginosa 1.57 X-RAY DIFFRACTION 100.0
4KOY TRANSFERASE 05/12/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cephalosporin C Pseudomonas aeruginosa 1.4 X-RAY DIFFRACTION 100.0
4KOT TRANSFERASE 05/12/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefotaxime Pseudomonas aeruginosa 1.55 X-RAY DIFFRACTION 100.0
5VDB transferase/transferase inhibitor 04/01/17 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 3 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.4 X-RAY DIFFRACTION 100.0
4KOS TRANSFERASE 05/12/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefmetazole Pseudomonas aeruginosa 1.55 X-RAY DIFFRACTION 100.0
4KOV TRANSFERASE 05/12/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefuroxime Pseudomonas aeruginosa 1.6 X-RAY DIFFRACTION 100.0
3PGP TRANSFERASE 11/02/10 Crystal structure of PA4794 - GNAT superfamily protein in complex with AcCoA Pseudomonas aeruginosa 1.42 X-RAY DIFFRACTION 100.0
5VD6 transferase/transferase inhibitor 04/01/17 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 6 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.2 X-RAY DIFFRACTION 100.0
4KLW TRANSFERASE 05/07/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 2-(aminocarbonyl)benzoate Pseudomonas aeruginosa 1.3 X-RAY DIFFRACTION 100.0
3KKW TRANSFERASE 11/06/09 Crystal structure of His-tagged form of PA4794 protein Pseudomonas aeruginosa PAO1 1.41 X-RAY DIFFRACTION 100.0
4M3S TRANSFERASE 08/06/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with HEPES Pseudomonas aeruginosa 1.3 X-RAY DIFFRACTION 100.0
4OAE TRANSFERASE 01/04/14 Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol Pseudomonas aeruginosa 1.25 X-RAY DIFFRACTION 98.1
4KOU TRANSFERASE 05/12/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefixime Pseudomonas aeruginosa 1.6 X-RAY DIFFRACTION 100.0
4KLV TRANSFERASE 05/07/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 4-methylumbelliferyl phosphate Pseudomonas aeruginosa 1.3 X-RAY DIFFRACTION 100.0
4KOW TRANSFERASE 05/12/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefoxitin Pseudomonas aeruginosa 1.45 X-RAY DIFFRACTION 100.0
4L8A TRANSFERASE 06/16/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in ternary complex with N-Phenylacetyl-Gly-AcLys and CoA Pseudomonas aeruginosa 1.2 X-RAY DIFFRACTION 100.0
4KOX TRANSFERASE 05/12/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefalotin Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 100.0
4KOR TRANSFERASE 05/12/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 7-aminocephalosporanic acid Pseudomonas aeruginosa 1.25 X-RAY DIFFRACTION 100.0
4OAD TRANSFERASE 01/04/14 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with chloramphenicol Pseudomonas aeruginosa 1.45 X-RAY DIFFRACTION 100.0
4L89 TRANSFERASE 06/16/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with covalently bound CoA Pseudomonas aeruginosa 1.6 X-RAY DIFFRACTION 100.0
4KUA TRANSFERASE 05/21/13 Crystal structure of a GNAT superfamily acetyltransferase PA4794 Pseudomonas aeruginosa 1.5 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 18 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004432 (386 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_25445

Human Homologs

References

No references are associated with this feature.