Pseudomonas aeruginosa DK2, PADK2_25980
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa DK2
GCF_000271365.1|latest |
| Locus Tag |
PADK2_25980
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 5594547 - 5595800 (- strand) |
Cross-References
| RefSeq | YP_006485161.1 |
| GI | 392986574 |
| Entrez | 13170567 |
| NCBI Locus Tag | PADK2_25980 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
vanillate porin OpdK
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 1.90 |
| Kyte-Doolittle Hydrophobicity Value | -0.372 |
| Molecular Weight (kDa) | 45.8 |
| Isoelectric Point (pI) | 7.79 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 2QTK | MEMBRANE PROTEIN | 08/02/07 | Crystal Structure of the outer membrane protein opdK from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 99.7 |
| 2Y2X | MEMBRANE PROTEIN | 12/16/10 | Crystal Structure of Pseudomonas Aeruginosa OpdK with Vanillate | PSEUDOMONAS AERUGINOSA PA01 | 1.65 | X-RAY DIFFRACTION | 99.7 |
| 3SYS | MEMBRANE PROTEIN | 07/18/11 | Improved crystal structure of Pseudomonas aeruginosa OccK1 (OpdK) | Pseudomonas aeruginosa | 1.65 | X-RAY DIFFRACTION | 99.7 |
Drugs Targeting this Protein
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
| Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
| (Hydroxyethyloxy)Tri(Ethyloxy)Octane | DB04233 | DrugBank | 5.1.4 | Q9HUR5 | Vanillate porin OpdK | 99.8 | 417 | 1.8e-244 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 20 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000239 (1158 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PADK2_25980
Search term: vanillate porin OpdK
|
Human Homologs
References
No references are associated with this feature.