Pseudomonas aeruginosa RP73, M062_04545
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa RP73
GCF_000414035.1|latest |
| Locus Tag |
M062_04545
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 975121 - 976110 (- strand) |
Cross-References
| RefSeq | YP_008131361.1 |
| GI | 514408458 |
| EC Number | 1.1.1.28 |
| Entrez | 15958652 |
| NCBI Locus Tag | M062_04545 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
D-lactate dehydrogenase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -4.72 |
| Kyte-Doolittle Hydrophobicity Value | 0.040 |
| Molecular Weight (kDa) | 35.8 |
| Isoelectric Point (pI) | 6.39 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 5Z20 | OXIDOREDUCTASE | 12/28/17 | The ternary structure of D-lactate dehydrogenase from Pseudomonas aeruginosa with NADH and oxamate | Pseudomonas aeruginosa | 2.2 | X-RAY DIFFRACTION | 99.7 |
| 6ABJ | OXIDOREDUCTASE | 07/21/18 | The apo-structure of D-lactate dehydrogenase from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.86 | X-RAY DIFFRACTION | 99.7 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 640 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000893 (1006 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: M062_04545
Search term: D-lactate dehydrogenase
|
Human Homologs
References
No references are associated with this feature.