Strain |
Pseudomonas aeruginosa RP73
GCF_000414035.1|latest |
Locus Tag |
M062_08470
|
Name |
|
Replicon | chromosome |
Genomic location | 1787449 - 1788885 (+ strand) |
RefSeq | YP_008132138.1 |
GI | 514409040 |
EC Number | 1.8.1.4 |
Entrez | 15959437 |
NCBI Locus Tag | M062_08470 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
dihydrolipoamide dehydrogenase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -0.22 |
Kyte-Doolittle Hydrophobicity Value | 0.135 |
Molecular Weight (kDa) | 50.2 |
Isoelectric Point (pI) | 6.96 |
Individual Mappings | |
Additional evidence for subcellular localization |
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
1LPF | OXIDOREDUCTASE | 10/26/92 | THREE-DIMENSIONAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM PSEUDOMONAS FLUORESCENS AT 2.8 ANGSTROMS RESOLUTION. ANALYSIS OF REDOX AND THERMOSTABILITY PROPERTIES | Pseudomonas fluorescens | 2.8 | X-RAY DIFFRACTION | 99.8 |
5U8W | OXIDOREDUCTASE | 12/15/16 | Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa bound to NADH | Pseudomonas aeruginosa (strain UCBPP-PA14) | 1.79 | X-RAY DIFFRACTION | 100.0 |
5U8V | OXIDOREDUCTASE | 12/15/16 | Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa bound to NAD+ | Pseudomonas aeruginosa (strain UCBPP-PA14) | 1.45 | X-RAY DIFFRACTION | 100.0 |
5U8U | OXIDOREDUCTASE | 12/15/16 | Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain UCBPP-PA14) | 1.35 | X-RAY DIFFRACTION | 100.0 |
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
Flavin adenine dinucleotide | DB03147 | DrugBank | 5.1.4 | P14218 | Dihydrolipoyl dehydrogenase | 99.8 | 478 | 1.6e-265 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 650 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003776 (538 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: M062_08470
Search term: dihydrolipoamide dehydrogenase
|
Ensembl
110, assembly
GRCh38.p14
|
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value:
1.1e-120
Percent Identity:
49.8
|
Ensembl
110, assembly
GRCh38.p14
|
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value:
1.1e-120
Percent Identity:
49.8
|