Pseudomonas aeruginosa RP73, M062_11085 (ligD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa RP73
GCF_000414035.1|latest
Locus Tag
M062_11085
Name
ligD
Replicon chromosome
Genomic location 2369617 - 2372139 (+ strand)

Cross-References

RefSeq YP_008132651.1
GI 514412984
EC Number 6.5.1.1
Entrez 15959958
NCBI Locus Tag M062_11085

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP-dependent DNA ligase
Synonyms
Evidence for Translation
Charge (pH 7) 18.97
Kyte-Doolittle Hydrophobicity Value -0.533
Molecular Weight (kDa) 94.0
Isoelectric Point (pI) 9.72

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2FAQ HYDROLASE/TRANSFERASE 12/07/05 Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with ATP and Manganese Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 99.7
3N9B LIGASE 05/28/10 Crystal Structure of the P. aeruginosa LigD phosphoesterase domain Pseudomonas aeruginosa 1.92 X-RAY DIFFRACTION 99.4
3N9D LIGASE 05/28/10 Monoclinic Structure of P. aeruginosa LigD phosphoesterase domain Pseudomonas aeruginosa 2.3 X-RAY DIFFRACTION 99.4
2FAO HYDROLASE/TRANSFERASE 12/07/05 Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain Pseudomonas aeruginosa 1.5 X-RAY DIFFRACTION 99.7
2FAR Hydrolase/Transferase 12/07/05 Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with dATP and Manganese Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 99.7
2LJ6 DNA BINDING PROTEIN 09/06/11 Solution Structure and DNA-binding Properties of the Phosphoesterase Domain of DNA Ligase D Pseudomonas aeruginosa NOT SOLUTION NMR 99.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 288 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003336 (490 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M062_11085
Search term: ligD

Human Homologs

References

No references are associated with this feature.