Pseudomonas aeruginosa RP73, M062_20550

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa RP73
GCF_000414035.1|latest
Locus Tag
M062_20550
Name
Replicon chromosome
Genomic location 4417848 - 4418504 (+ strand)

Cross-References

RefSeq YP_008134517.1
GI 514411076
Entrez 15961848
NCBI Locus Tag M062_20550

Product

Feature Type CDS
Coding Frame 1
Product Name
protein tyrosine/serine phosphatase
Synonyms
Evidence for Translation
Charge (pH 7) 0.59
Kyte-Doolittle Hydrophobicity Value -0.111
Molecular Weight (kDa) 24.0
Isoelectric Point (pI) 7.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4R0T HYDROLASE 08/01/14 Crystal structure of P. aeruginosa TpbA (C132S) in complex with pTyr Pseudomonas aeruginosa PAO1 2.603 X-RAY DIFFRACTION 99.5
4R0S HYDROLASE 08/01/14 Crystal structure of P. aeruginosa TpbA Pseudomonas aeruginosa PAO1 2.03 X-RAY DIFFRACTION 100.0
2M3V HYDROLASE 01/26/13 Solution structure of tyrosine phosphatase related to biofilm formation A (TpbA) from Pseudomonas aeruginosa Pseudomonas aeruginosa NOT SOLUTION NMR 97.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 32 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001786 (406 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M062_20550

Human Homologs

References

No references are associated with this feature.