Pseudomonas aeruginosa RP73, M062_21810

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa RP73
GCF_000414035.1|latest
Locus Tag
M062_21810
Name
Replicon chromosome
Genomic location 4690597 - 4691805 (- strand)

Cross-References

RefSeq YP_008134769.1
GI 514411309
Entrez 15962100
NCBI Locus Tag M062_21810

Product

Feature Type CDS
Coding Frame 1
Product Name
MFS transporter
Synonyms
Evidence for Translation
Charge (pH 7) 12.88
Kyte-Doolittle Hydrophobicity Value 0.963
Molecular Weight (kDa) 41.8
Isoelectric Point (pI) 9.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
bcr-1 Transmembrane protein which expels bicyclomycin from the cell, leading to bicyclomycin resistance. Identified in Pseudomonas aeruginosa strains responsible for outbreaks in Brazil, often appearing with blaSPM-1, another bicyclomycin resistance gene. [PMID:25085655, PMID:26093374] ARO:3003801 protein homolog model Strict 753.1 99.5 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 560 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001563 (351 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M062_21810
Search term: MFS transporter

Human Homologs

References

No references are associated with this feature.