Pseudomonas aeruginosa RP73, M062_28315

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa RP73
GCF_000414035.1|latest
Locus Tag
M062_28315
Name
Replicon chromosome
Genomic location 6125620 - 6127092 (- strand)

Cross-References

RefSeq YP_008136032.1
GI 514412478
Entrez 15963401
NCBI Locus Tag M062_28315

Product

Feature Type CDS
Coding Frame 1
Product Name
betaine-aldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -10.65
Kyte-Doolittle Hydrophobicity Value -0.146
Molecular Weight (kDa) 53.3
Isoelectric Point (pI) 5.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4CAZ OXIDOREDUCTASE 10/09/13 CRYSTAL STRUCTURE OF BETAINE ALDEHYDE DEHYDROGENASE FROM Pseudomonas aeruginosa IN COMPLEX WITH NADH PSEUDOMONAS AERUGINOSA 2.55 X-RAY DIFFRACTION 100.0
2WOX OXIDOREDUCTASE 07/30/09 Betaine aldehyde dehydrogenase from Pseudomonas aeruginosa with NAD(P) H-catalytic thiol adduct. PSEUDOMONAS AERUGINOSA 2.3 X-RAY DIFFRACTION 100.0
2WME OXIDOREDUCTASE 06/30/09 Crystallographic structure of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 2.1 X-RAY DIFFRACTION 100.0
6BJP OXIDOREDUCTASE 11/06/17 Apo form of the E124S mutant of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.102 X-RAY DIFFRACTION 99.8
4CBB OXIDOREDUCTASE 10/11/13 APO FORM OF BETAINE ALDEHYDE DEHYDROGENASE FROM Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 100.0
6BPG OXIDOREDUCTASE 11/23/17 Crystal structure of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa with bound rubidium ions Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.086 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 607 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004938 (527 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M062_28315

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412]
E-value: 5.7e-141
Percent Identity: 52.9

References

No references are associated with this feature.