Pseudomonas stutzeri A1501, PST_1877 (lpdG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas stutzeri A1501
GCF_000013785.1|latest
Locus Tag
PST_1877
Name
lpdG
Replicon chromosome
Genomic location 2027314 - 2028750 (+ strand)

Cross-References

RefSeq YP_001172393.1
GI 146282240
EC Number 1.8.1.4
Entrez 5097961
INSDC ABP79551.1
NCBI Locus Tag PST_1877
UniParc UPI00014FF3D7
UniProtKB Acc A4VKQ0
UniProtKB ID A4VKQ0_PSEU5
UniRef100 UniRef100_A4VKQ0
UniRef50 UniRef50_P31052
UniRef90 UniRef90_A0A098FPG4

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrolipoamide dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -7.22
Kyte-Doolittle Hydrophobicity Value 0.158
Molecular Weight (kDa) 49.9
Isoelectric Point (pI) 5.94

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Flavin adenine dinucleotide DB03147 DrugBank 5.1.4 P18925 Dihydrolipoyl dehydrogenase 86.6 477 5.7e-234

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 649 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003776 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PST_1877
Search term: lpdG

Human Homologs

Ensembl 110, assembly GRCh38.p14
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 4.1e-120
Percent Identity: 48.7
Ensembl 110, assembly GRCh38.p14
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 4.1e-120
Percent Identity: 48.7

References

No references are associated with this feature.