Pseudomonas stutzeri A1501, PST_2034 (prpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas stutzeri A1501
GCF_000013785.1|latest
Locus Tag
PST_2034
Name
prpB
Replicon chromosome
Genomic location 2208259 - 2209146 (+ strand)

Cross-References

RefSeq YP_001172547.1
GI 146282394
EC Number 4.1.3.30
Entrez 5098117
INSDC ABP79705.1
NCBI Locus Tag PST_2034
UniParc UPI00014FEDC1
UniProtKB Acc A4VL54
UniProtKB ID A4VL54_PSEU5
UniRef100 UniRef100_A4VL54
UniRef50 UniRef50_Q56062
UniRef90 UniRef90_Q88KF6

Product

Feature Type CDS
Coding Frame 1
Product Name
2-methylisocitrate lyase
Synonyms
Evidence for Translation
Charge (pH 7) -4.65
Kyte-Doolittle Hydrophobicity Value 0.027
Molecular Weight (kDa) 31.9
Isoelectric Point (pI) 5.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6T4V LYASE 10/15/19 Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in apo form. Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.807 X-RAY DIFFRACTION 91.4
6T5M LYASE 10/16/19 Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in complex with Mg(II)-pyruvate. Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.76 X-RAY DIFFRACTION 91.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 345 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000769 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PST_2034
Search term: prpB

Human Homologs

References

No references are associated with this feature.