Pseudomonas stutzeri A1501, PST_2622 (fabG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas stutzeri A1501
GCF_000013785.1|latest
Locus Tag
PST_2622
Name
fabG
Replicon chromosome
Genomic location 2841281 - 2842024 (- strand)

Cross-References

RefSeq YP_001173114.1
GI 146282961
EC Number 1.1.1.100
Entrez 5095584
INSDC ABP80272.1
NCBI Locus Tag PST_2622
UniParc UPI00014FECF9
UniProtKB Acc A4VMS1
UniProtKB ID A4VMS1_PSEU5
UniRef100 UniRef100_A4VMS1
UniRef50 UniRef50_P0AEK2
UniRef90 UniRef90_I4CV97

Product

Feature Type CDS
Coding Frame 1
Product Name
3-ketoacyl-ACP reductase
Synonyms
Evidence for Translation
Charge (pH 7) -0.52
Kyte-Doolittle Hydrophobicity Value 0.048
Molecular Weight (kDa) 25.8
Isoelectric Point (pI) 6.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4BO0 OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(4-methoxy-1- methylindazol-3-yl)-3-(2-methoxyphenyl)urea at 2.4A resolution PSEUDOMONAS AERUGINOSA 2.4 X-RAY DIFFRACTION 90.3
4BNT OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2-(trifluoromethyl)-1H- benzimidazole at 2.3A resolution PSEUDOMONAS AERUGINOSA 2.3 X-RAY DIFFRACTION 90.3
4BNU OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2-phenyl-4-(1,2,4- triazol-4-yl)quinazoline at 2.0A resolution PSEUDOMONAS AERUGINOSA 2 X-RAY DIFFRACTION 90.3
4BO2 OXIDOREDUCTASE 05/18/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(1-ethylbenzimidazol-2- yl)-3-(2-methoxyphenyl)urea at 1.9A resolution PSEUDOMONAS AERUGINOSA 1.9 X-RAY DIFFRACTION 90.3
4BO3 OXIDOREDUCTASE 05/18/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2-(3-(trifluoromethyl) anilino)pyridine-3-sulfonamide at 2.5A resolution PSEUDOMONAS AERUGINOSA 2.5 X-RAY DIFFRACTION 90.3
4AG3 OXIDOREDUCTASE 01/24/12 Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with NADPH at 1.8A resolution PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 90.3
4BNY OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 4-(2-phenylthieno(3,2-d) pyrimidin-4-yl)morpholine at 1.8A resolution PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 90.3
4AFN OXIDOREDUCTASE 01/20/12 Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa at 2.3A resolution PSEUDOMONAS AERUGINOSA 2.3 X-RAY DIFFRACTION 90.3
4BNX OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 6-(4-(2-chloroanilino)- 1H-quinazolin-2-ylidene)cyclohexa-2, 4-dien-1-one at 2.3A resolution PSEUDOMONAS AERUGINOSA 2.3 X-RAY DIFFRACTION 90.3
4BO1 OXIDOREDUCTASE 05/18/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with N-(4-chloro-2,5- dimethoxyphenyl)quinoline-8-carboxamide at 2.2A resolution PSEUDOMONAS AERUGINOSA 2.2 X-RAY DIFFRACTION 90.3

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002615 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PST_2622
Search term: fabG

Human Homologs

Ensembl 110, assembly GRCh38.p14
carbonyl reductase 4 [Source:HGNC Symbol;Acc:HGNC:25891]
E-value: 6.8e-42
Percent Identity: 42.3

References

No references are associated with this feature.