Pseudomonas stutzeri DSM 4166, PSTAA_3761 (hfq)

Gene Feature Overview

Strain	Pseudomonas stutzeri DSM 4166 GCF_000195105.1|latest
Locus Tag	PSTAA_3761
Name	hfq
Replicon	chromosome
Genomic location	4023725 - 4023979 (- strand)

Cross-References

RefSeq	YP_005940359.1
GI	386022334
Entrez	12530911
INSDC	AEA85617.1
NCBI Locus Tag	PSTAA_3761
UniParc	UPI00014FF1BF
UniProtKB Acc	F2N194
UniProtKB ID	F2N194_PSEU6
UniRef100	UniRef100_A4VQP0
UniRef50	UniRef50_Q0C0N8
UniRef90	UniRef90_A4XPY7

Product

Feature Type	CDS
Coding Frame	1
Product Name	RNA-binding protein Hfq
Synonyms
Evidence for Translation
Charge (pH 7)	1.46
Kyte-Doolittle Hydrophobicity Value	-0.296
Molecular Weight (kDa)	9.3
Isoelectric Point (pI)	8.99

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
8BVM	RNA BINDING PROTEIN	12/04/22	Cryo-EM structure of Hfq-Crc-rbsB translation repression complex	Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT	3.8	ELECTRON MICROSCOPY	90.4
8BVJ	RNA BINDING PROTEIN	12/04/22	Hfq-Crc-estA translation repression complex	Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT	4.5	ELECTRON MICROSCOPY	90.4
4J5Y	RNA BINDING PROTEIN	02/11/13	Crystal structure of Hfq from Pseudomonas aeruginosa in complex with ATP	Pseudomonas aeruginosa	2.0953	X-RAY DIFFRACTION	90.4
3QUI	RNA BINDING PROTEIN	02/24/11	Crystal structure of Pseudomonas aeruginosa Hfq in complex with ADPNP	Pseudomonas aeruginosa	1.933	X-RAY DIFFRACTION	90.4
8BVH	RNA BINDING PROTEIN	12/03/22	Cryo-EM structure of the Hfq-Crc-amiE translation repression assembly.	Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT	3.6	ELECTRON MICROSCOPY	90.4

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 282 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004559 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSTAA_3761 Search term: hfq Search term: RNA-binding protein Hfq

Human Homologs

References