Pseudomonas stutzeri DSM 4166, PSTAA_3786

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas stutzeri DSM 4166
GCF_000195105.1|latest
Locus Tag
PSTAA_3786
Name
Replicon chromosome
Genomic location 4051674 - 4053200 (+ strand)

Cross-References

RefSeq YP_005940385.1
GI 386022360
Entrez 12530938
INSDC AEA85642.1
NCBI Locus Tag PSTAA_3786
UniParc UPI0002047855
UniProtKB Acc F2N1C0
UniProtKB ID F2N1C0_PSEU6
UniRef100 UniRef100_F2N1C0
UniRef50 UniRef50_N0CME8
UniRef90 UniRef90_A4VQS0

Product

Feature Type CDS
Coding Frame 1
Product Name
tyrosine decarboxylase
Synonyms
Evidence for Translation
Charge (pH 7) -1.90
Kyte-Doolittle Hydrophobicity Value -0.095
Molecular Weight (kDa) 55941.0
Isoelectric Point (pI) 6.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Pyridoxal phosphate DB00114 DrugBank 5.1.4 Q9UGI5 Glutamic acid decarboxylase 28.9 426 7.9e-46
Phenelzine DB00780 DrugBank 5.1.4 Q9UGI5 Glutamic acid decarboxylase 28.9 426 7.9e-46

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 297 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG015765 (72 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSTAA_3786

Human Homologs

Ensembl 110, assembly GRCh38.p14
glutamate decarboxylase 2 [Source:HGNC Symbol;Acc:HGNC:4093]
E-value: 2.1e-45
Percent Identity: 28.9
Ensembl 110, assembly GRCh38.p14
glutamate decarboxylase 2 [Source:HGNC Symbol;Acc:HGNC:4093]
E-value: 2.1e-45
Percent Identity: 28.9
Ensembl 110, assembly GRCh38.p14
glutamate decarboxylase 2 [Source:HGNC Symbol;Acc:HGNC:4093]
E-value: 2.1e-45
Percent Identity: 28.9

References

No references are associated with this feature.