Pseudomonas stutzeri CCUG 29243, A458_02195 (aceF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas stutzeri CCUG 29243
GCF_000267545.1|latest
Locus Tag
A458_02195
Name
aceF
Replicon chromosome
Genomic location 475961 - 477967 (- strand)

Cross-References

RefSeq YP_006456118.1
GI 392419514
EC Number 2.3.1.12
Entrez 13145219
INSDC AFM31695.1
NCBI Locus Tag A458_02195
UniParc UPI0002660C8E
UniProtKB Acc I4CNN8
UniProtKB ID I4CNN8_PSEST
UniRef100 UniRef100_I4CNN8
UniRef50 UniRef50_P10802
UniRef90 UniRef90_F2N4Q1

Product

Feature Type CDS
Coding Frame 1
Product Name
pyruvate dehydrogenase dihydrolipoyltransacetylase
Synonyms
Evidence for Translation
Charge (pH 7) -23.07
Kyte-Doolittle Hydrophobicity Value -0.112
Molecular Weight (kDa) 69068.9
Isoelectric Point (pI) 4.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1DPD DIHYDROLIPOAMIDE ACETYLTRANSFERASE 02/03/95 CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P) Azotobacter vinelandii 2.7 X-RAY DIFFRACTION 90.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 524 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004623 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A458_02195
Search term: aceF

Human Homologs

Ensembl 110, assembly GRCh38.p14
dihydrolipoamide S-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2896]
E-value: 1.1e-33
Percent Identity: 33.2
Ensembl 110, assembly GRCh38.p14
dihydrolipoamide S-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2896]
E-value: 1.1e-33
Percent Identity: 33.2
Ensembl 110, assembly GRCh38.p14
dihydrolipoamide S-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2896]
E-value: 1.1e-33
Percent Identity: 33.2
Ensembl 110, assembly GRCh38.p14
dihydrolipoamide S-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2896]
E-value: 1.1e-33
Percent Identity: 33.2
Ensembl 110, assembly GRCh38.p14
dihydrolipoamide S-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2896]
E-value: 1.1e-33
Percent Identity: 33.2

References

No references are associated with this feature.