Pseudomonas stutzeri CCUG 29243, A458_14725 (aspS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas stutzeri CCUG 29243
GCF_000267545.1|latest
Locus Tag
A458_14725
Name
aspS
Replicon chromosome
Genomic location 3206158 - 3207933 (- strand)

Cross-References

RefSeq YP_006458597.1
GI 392421993
EC Number 6.1.1.12
Entrez 13148563
NCBI Locus Tag A458_14725

Product

Feature Type CDS
Coding Frame 1
Product Name
aspartyl-tRNA ligase
Synonyms
Evidence for Translation
Charge (pH 7) -14.46
Kyte-Doolittle Hydrophobicity Value -0.239
Molecular Weight (kDa) 66006.8
Isoelectric Point (pI) 5.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4WJ4 LIGASE/RNA 09/29/14 Crystal structure of non-discriminating aspartyl-tRNA synthetase from Pseudomonas aeruginosa complexed with tRNA(Asn) and aspartic acid Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 3.294 X-RAY DIFFRACTION 91.8
4WJ3 LIGASE/RNA 09/29/14 Crystal structure of the asparagine transamidosome from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 3.705 X-RAY DIFFRACTION 91.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000928 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A458_14725
Search term: aspS

Human Homologs

Ensembl 110, assembly GRCh38.p14
aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]
E-value: 4.4e-116
Percent Identity: 40.2

References

No references are associated with this feature.