Pseudomonas stutzeri CCUG 29243, A458_17640 (ribH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas stutzeri CCUG 29243
GCF_000267545.1|latest
Locus Tag
A458_17640
Name
ribH
Replicon chromosome
Genomic location 3797213 - 3797689 (- strand)

Cross-References

RefSeq YP_006459176.1
GI 392422572
Entrez 13146112
INSDC AFM34753.1
NCBI Locus Tag A458_17640
UniParc UPI0002601CA8
UniProtKB Acc I4CXE6
UniProtKB ID I4CXE6_PSEST
UniRef100 UniRef100_A0A023WWY2
UniRef50 UniRef50_P45149
UniRef90 UniRef90_Q889Q6

Product

Feature Type CDS
Coding Frame 1
Product Name
6,7-dimethyl-8-ribityllumazine synthase
Synonyms
Evidence for Translation
Charge (pH 7) -4.56
Kyte-Doolittle Hydrophobicity Value 0.354
Molecular Weight (kDa) 16.5
Isoelectric Point (pI) 4.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
5-Nitro-6-Ribityl-Amino-2,4(1h,3h)-Pyrimidinedione DB04162 DrugBank 5.1.4 P11998 6,7-dimethyl-8-ribityllumazine synthase 53.2 154 4.8e-41

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 612 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001631 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A458_17640
Search term: ribH

Human Homologs

References

No references are associated with this feature.