Pseudomonas stutzeri CCUG 29243, A458_19310 (thyA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas stutzeri CCUG 29243
GCF_000267545.1|latest
Locus Tag
A458_19310
Name
thyA
Replicon chromosome
Genomic location 4152143 - 4152937 (- strand)

Cross-References

RefSeq YP_006459508.1
GI 392422904
EC Number 2.1.1.45
Entrez 13146375
INSDC AFM35085.1
NCBI Locus Tag A458_19310
UniParc UPI0002660345
UniProtKB Acc I4CYC8
UniProtKB ID I4CYC8_PSEST
UniRef100 UniRef100_I4CYC8
UniRef50 UniRef50_P11044
UniRef90 UniRef90_A4VGL9

Product

Feature Type CDS
Coding Frame 1
Product Name
thymidylate synthase
Synonyms
Evidence for Translation
Charge (pH 7) -4.75
Kyte-Doolittle Hydrophobicity Value -0.186
Molecular Weight (kDa) 30.2
Isoelectric Point (pI) 6.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 396 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000334 (395 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A458_19310
Search term: thyA

Human Homologs

Ensembl 110, assembly GRCh38.p14
thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441]
E-value: 9.6e-79
Percent Identity: 50.0

References

No references are associated with this feature.