Pseudomonas mendocina NK-01, MDS_2137

Gene Feature Overview

Strain	Pseudomonas mendocina NK-01 GCF_000204295.1|latest
Locus Tag	MDS_2137
Name
Replicon	chromosome
Genomic location	2349335 - 2350471 (- strand)

Cross-References

RefSeq	YP_004379920.1
GI	330503051
Entrez	10456919
INSDC	AEB58168.1
NCBI Locus Tag	MDS_2137
UniParc	UPI000206DE59
UniProtKB Acc	F4DR85
UniProtKB ID	F4DR85_PSEMN
UniRef100	UniRef100_F4DR85
UniRef50	UniRef50_P85302
UniRef90	UniRef90_F4DR85

Product

Feature Type	CDS
Coding Frame	1
Product Name	beta-lactamase
Synonyms
Evidence for Translation
Charge (pH 7)	1.65
Kyte-Doolittle Hydrophobicity Value	-0.171
Molecular Weight (kDa)	41536.9
Isoelectric Point (pI)	7.76

Subcellular localization

Individual Mappings	Localization Confidence PMID Periplasmic Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
PRC-1	PRC-1 is a beta-lactamase that confers resistance to certain cephalosporins and penicillins. [PMID:34975778]	ARO:3007085	protein homolog model		Strict	656.4	86.81	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 264 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001588 (493 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: MDS_2137 Search term: beta-lactamase

Human Homologs

References