Pseudomonas mendocina NK-01, MDS_4294

Gene Feature Overview

Strain	Pseudomonas mendocina NK-01 GCF_000204295.1|latest
Locus Tag	MDS_4294
Name
Replicon	chromosome
Genomic location	4693263 - 4693574 (- strand)

Cross-References

RefSeq	YP_004382077.1
GI	330505208
Entrez	10459076
INSDC	AEB60325.1
NCBI Locus Tag	MDS_4294
UniParc	UPI0000526BF2
UniProtKB Acc	F4DLE3
UniProtKB ID	F4DLE3_PSEMN
UniRef100	UniRef100_C1DKL2
UniRef50	UniRef50_P19460
UniRef90	UniRef90_B4RZN1

Product

Feature Type	CDS
Coding Frame	1
Product Name	30S ribosomal protein S10
Synonyms
Evidence for Translation
Charge (pH 7)	4.71
Kyte-Doolittle Hydrophobicity Value	-0.528
Molecular Weight (kDa)	11.8
Isoelectric Point (pI)	10.31

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
7UNR	RIBOSOME	04/11/22	Pseudomonas aeruginosa 70S ribosome initiation complex bound to compact IF2-GDP (composite structure I-A)	Escherichia coli; Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT	2.9	ELECTRON MICROSCOPY	99.0
7UNW	RIBOSOME	04/11/22	Pseudomonas aeruginosa 70S ribosome initiation complex bound to IF2-GDPCP (structure II-B)	Escherichia coli; Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT	2.6	ELECTRON MICROSCOPY	99.0
7UNU	RIBOSOME	04/11/22	Pseudomonas aeruginosa 70S ribosome initiation complex bound to compact IF2-GDP (composite structure I-B)	Escherichia coli; Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT	2.9	ELECTRON MICROSCOPY	99.0
6SPC	RIBOSOME	09/01/19	Pseudomonas aeruginosa 30s ribosome from an aminoglycoside resistant clinical isolate	Pseudomonas aeruginosa	2.95	ELECTRON MICROSCOPY	99.0
7UNV	RIBOSOME	04/11/22	Pseudomonas aeruginosa 70S ribosome initiation complex bound to IF2-GDPCP (structure II-A)	Escherichia coli; Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT	2.7	ELECTRON MICROSCOPY	99.0
6SPE	RIBOSOME	09/01/19	Pseudomonas aeruginosa 30s ribosome from a clinical isolate	Pseudomonas aeruginosa	3.6	ELECTRON MICROSCOPY	99.0
6SPF	RIBOSOME	09/01/19	Pseudomonas aeruginosa 70s ribosome from an aminoglycoside resistant clinical isolate	Pseudomonas aeruginosa	2.89	ELECTRON MICROSCOPY	99.0
6SPG	RIBOSOME	09/01/19	Pseudomonas aeruginosa 70s ribosome from a clinical isolate	Pseudomonas aeruginosa	3.34	ELECTRON MICROSCOPY	99.0

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name	Source Accession	Source DB	Version	Target Accession	Target Description	Percent Identity	Alignment Length	E-Value
Nitrofurantoin	DB00698	DrugBank	5.1.4	P0A7R5	30S ribosomal protein S10	89.3	103	6.2e-45

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 664 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001446 (528 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: MDS_4294 Search term: 30S ribosomal protein S10

Human Homologs

References