Pseudomonas mendocina NK-01, MDS_4295

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas mendocina NK-01
GCF_000204295.1|latest
Locus Tag
MDS_4295
Name
Replicon chromosome
Genomic location 4693730 - 4694923 (- strand)

Cross-References

RefSeq YP_004382078.1
GI 330505209
Entrez 10459077
NCBI Locus Tag MDS_4295

Product

Feature Type CDS
Coding Frame 1
Product Name
elongation factor Tu
Synonyms
Evidence for Translation
Charge (pH 7) -10.75
Kyte-Doolittle Hydrophobicity Value -0.162
Molecular Weight (kDa) 43.5
Isoelectric Point (pI) 5.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4J0Q TRANSLATION 01/31/13 Crystal structure of Pseudomonas putida elongation factor Tu (EF-Tu) Pseudomonas putida 2.294 X-RAY DIFFRACTION 92.2
4IW3 METAL BINDING PROTEIN/TRANSLATION 01/23/13 Crystal structure of a Pseudomonas putida prolyl-4-hydroxylase (P4H) in complex with elongation factor Tu (EF-Tu) Pseudomonas putida 2.697 X-RAY DIFFRACTION 92.2
4ZV4 TRANSLATION 05/18/15 Structure of Tse6 in complex with EF-Tu Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 3.504 X-RAY DIFFRACTION 90.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001434 (870 members)
Putative Inparalogs 1 predicted inparalogs
elongation factor Tu (MDS_4307) 100.0% identity

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: MDS_4295

Human Homologs

Ensembl 110, assembly GRCh38.p14
Tu translation elongation factor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:12420]
E-value: 5.1e-132
Percent Identity: 55.4

References

No references are associated with this feature.