Pseudomonas brassicacearum subsp. brassicacearum NFM421, PSEBR_a4253

Gene Feature Overview

Strain	Pseudomonas brassicacearum subsp. brassicacearum NFM421 GCF_000194805.1|latest
Locus Tag	PSEBR_a4253
Name
Replicon	chromosome
Genomic location	5178481 - 5179539 (+ strand)

Cross-References

RefSeq	YP_004355665.1
GI	330811203
Entrez	10473410
INSDC	AEA70661.1
NCBI Locus Tag	PSEBR_a4253
UniParc	UPI0002041827
UniProtKB Acc	F2KKK5
UniProtKB ID	F2KKK5_PSEBN
UniRef100	UniRef100_G8Q5L6
UniRef50	UniRef50_Q8XAC5
UniRef90	UniRef90_Q4K8A5

Product

Feature Type	CDS
Coding Frame	1
Product Name	phosphoribosylformylglycinamidine cyclo-ligase
Synonyms
Evidence for Translation
Charge (pH 7)	-12.79
Kyte-Doolittle Hydrophobicity Value	0.155
Molecular Weight (kDa)	36.9
Isoelectric Point (pI)	4.66

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 596 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000911 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSEBR_a4253 Search term: phosphoribosylformylglycinamidine cyclo-ligase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000371236 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163] E-value: 9.8e-95 Percent Identity: 50.4
Ensembl 110, assembly GRCh38.p14	ENSP00000371253 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163] E-value: 9.8e-95 Percent Identity: 50.4
Ensembl 110, assembly GRCh38.p14	ENSP00000371261 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163] E-value: 9.8e-95 Percent Identity: 50.4

References