Pseudomonas denitrificans ATCC 13867, H681_16980

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas denitrificans ATCC 13867
GCF_000349845.1|latest
Locus Tag
H681_16980
Name
Replicon chromosome
Genomic location 3835190 - 3835867 (+ strand)

Cross-References

RefSeq YP_007658804.1
GI 472326558
Entrez 14997522
INSDC AGI25264.1
NCBI Locus Tag H681_16980
UniParc UPI0002C4E717
UniProtKB Acc M4WZL9
UniProtKB ID M4WZL9_PSEDE
UniRef100 UniRef100_M4WZL9
UniRef50 UniRef50_Q4KGB4
UniRef90 UniRef90_M4WZL9

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component response regulator
Synonyms
Evidence for Translation
Charge (pH 7) -1.86
Kyte-Doolittle Hydrophobicity Value -0.155
Molecular Weight (kDa) 24583.0
Isoelectric Point (pI) 6.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
Pseudomonas aeruginosa CpxR CpxR is directly involved in activation of expression of RND efflux pump MexAB-OprM in P. aeruginosa. CpxR is required to enhance mexAB-oprM expression and drug resistance, in the absence of repressor MexR. [PMID:27736975] ARO:3004054 protein homolog model Strict 409.1 91.52 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002411 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: H681_16980

Human Homologs

References

No references are associated with this feature.