Pseudomonas denitrificans ATCC 13867, H681_21720 (fis)

Gene Feature Overview

Strain	Pseudomonas denitrificans ATCC 13867 GCF_000349845.1|latest
Locus Tag	H681_21720
Name	fis
Replicon	chromosome
Genomic location	4855304 - 4855624 (+ strand)

Cross-References

RefSeq	YP_007659751.1
GI	472327505
Entrez	14998469
INSDC	AGI26211.1
NCBI Locus Tag	H681_21720
UniParc	UPI0002C4EF7D
UniProtKB Acc	M4X3Q8
UniProtKB ID	M4X3Q8_PSEDE
UniRef100	UniRef100_M4X3Q8
UniRef50	UniRef50_Q9HUW0
UniRef90	UniRef90_Q9HUW0

Product

Feature Type	CDS
Coding Frame	1
Product Name	global DNA-binding transcriptional dual regulator Fis
Synonyms
Evidence for Translation
Charge (pH 7)	-1.33
Kyte-Doolittle Hydrophobicity Value	-0.371
Molecular Weight (kDa)	11836.5
Isoelectric Point (pI)	6.24

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6M10	DNA BINDING PROTEIN	02/24/20	Crystal structure of PA4853 (Fis) from Pseudomonas aeruginosa	Pseudomonas aeruginosa PAO1	2.985	X-RAY DIFFRACTION	97.1

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 197 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004482 (535 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: H681_21720 Search term: fis Search term: global DNA-binding transcriptional dual regulator Fis

Human Homologs

References