Pseudomonas denitrificans ATCC 13867, H681_22505

Gene Feature Overview

Strain	Pseudomonas denitrificans ATCC 13867 GCF_000349845.1|latest
Locus Tag	H681_22505
Name
Replicon	chromosome
Genomic location	5035561 - 5037204 (+ strand)

Cross-References

RefSeq	YP_007659908.1
GI	472327662
Entrez	14998626
INSDC	AGI26368.1
NCBI Locus Tag	H681_22505
UniParc	UPI0002C4E103
UniProtKB Acc	M4X1U7
UniProtKB ID	M4X1U7_PSEDE
UniRef100	UniRef100_M4X1U7
UniRef50	UniRef50_P10802
UniRef90	UniRef90_A0A024HNM0

Product

Feature Type	CDS
Coding Frame	1
Product Name	dihydrolipoamide acetyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-10.10
Kyte-Doolittle Hydrophobicity Value	0.099
Molecular Weight (kDa)	56058.0
Isoelectric Point (pI)	5.19

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
1EAE	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	12/16/92	ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX	Azotobacter vinelandii	2.6	X-RAY DIFFRACTION	90.1
1EAB	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	12/16/92	ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX	Azotobacter vinelandii	2.6	X-RAY DIFFRACTION	90.1
1EAD	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	12/16/92	ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX	Azotobacter vinelandii	2.6	X-RAY DIFFRACTION	90.1
1EAC	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	12/16/92	ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX	Azotobacter vinelandii	2.6	X-RAY DIFFRACTION	90.1
1EAF	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	12/16/92	ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX	Azotobacter vinelandii	2.6	X-RAY DIFFRACTION	90.1
1DPD	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	02/03/95	CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)	Azotobacter vinelandii	2.7	X-RAY DIFFRACTION	90.1
1DPB	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	02/03/95	CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)	Azotobacter vinelandii	2.5	X-RAY DIFFRACTION	90.1
1EAA	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	12/16/92	ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX	Azotobacter vinelandii	2.6	X-RAY DIFFRACTION	90.1
1DPC	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	02/03/95	CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)	Azotobacter vinelandii	2.6	X-RAY DIFFRACTION	90.1

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 523 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004623 (531 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: H681_22505 Search term: dihydrolipoamide acetyltransferase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000359151 dihydrolipoamide branched chain transacylase E2 [Source:HGNC Symbol;Acc:HGNC:2698] E-value: 1.4e-36 Percent Identity: 29.0

References