Pseudomonas aeruginosa LESB58, PALES_01581

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_01581
Name
Replicon chromosome
Genomic location 177283 - 178353 (+ strand)

Cross-References

RefSeq YP_002437766
GI 218888902
Entrez 7175277

Product

Feature Type CDS
Coding Frame 1
Product Name
putative Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.22
Kyte-Doolittle Hydrophobicity Value -0.246
Molecular Weight (kDa) 38.3
Isoelectric Point (pI) 9.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
TriB TriB is a membrane protein that is fused to TriA and both are required for the triclosan efflux pump function of TriABC-OpmH in P. aeruginosa. [PMID:17720796] ARO:3003680 protein homolog model Strict 665.2 99.72 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6VEJ TRANSPORT PROTEIN 01/02/20 TriABC transporter from Pseudomonas aeruginosa Pseudomonas aeruginosa 4.5 ELECTRON MICROSCOPY 98.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 415 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000155 (490 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_01581

Human Homologs

References

No references are associated with this feature.