Pseudomonas aeruginosa LESB58, PALES_07381

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_07381
Name
Replicon chromosome
Genomic location 805603 - 807093 (- strand)

Cross-References

RefSeq YP_002438346
GI 218889482
Entrez 7180728

Product

Feature Type CDS
Coding Frame 1
Product Name
putative aldehyde dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -13.53
Kyte-Doolittle Hydrophobicity Value -0.006
Molecular Weight (kDa) 53.4
Isoelectric Point (pI) 5.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7UYY OXIDOREDUCTASE 05/07/22 The crystal structure of the Pseudomonas aeruginosa aldehyde dehydrogenase encoded by the PA4189 gene in complex with NADH Pseudomonas aeruginosa PAO1 2.7 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 601 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001512 (334 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_07381

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777]
E-value: 1.6e-98
Percent Identity: 39.9
Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402]
E-value: 1.6e-98
Percent Identity: 41.2
Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777]
E-value: 1.6e-98
Percent Identity: 39.9

References

No references are associated with this feature.