Pseudomonas aeruginosa LESB58, PALES_24711 (aceA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_24711
Name
aceA
Replicon chromosome
Genomic location 2658845 - 2660440 (- strand)

Cross-References

RefSeq YP_002440071
GI 218891205
Entrez 7176968

Product

Feature Type CDS
Coding Frame 1
Product Name
isocitrate lyase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -8.85
Kyte-Doolittle Hydrophobicity Value -0.312
Molecular Weight (kDa) 58.9
Isoelectric Point (pI) 5.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6G1O LYASE 03/21/18 Structure of Pseudomonas aeruginosa Isocitrate Lyase, ICL Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.882 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 273 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002919 (354 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_24711
Search term: aceA
Search term: isocitrate lyase

Human Homologs

References

No references are associated with this feature.