Pseudomonas aeruginosa LESB58, PALES_43261 (pqsD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_43261
Name
pqsD
Replicon chromosome
Genomic location 4764405 - 4765418 (- strand)

Cross-References

RefSeq YP_002441910
GI 218893041
Entrez 7180726

Product

Feature Type CDS
Coding Frame 1
Product Name
3-oxoacyl-(acyl carrier protein) synthase III
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -9.53
Kyte-Doolittle Hydrophobicity Value 0.072
Molecular Weight (kDa) 36.4
Isoelectric Point (pI) 5.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3H78 TRANSFERASE 04/24/09 Crystal structure of Pseudomonas aeruginosa PqsD C112A mutant in complex with anthranilic acid Pseudomonas aeruginosa PAO1 1.7 X-RAY DIFFRACTION 99.4
3H77 TRANSFERASE 04/24/09 Crystal structure of Pseudomonas aeruginosa PqsD in a covalent complex with anthranilate Pseudomonas aeruginosa PAO1 1.8 X-RAY DIFFRACTION 99.7
3H76 TRANSFERASE 04/24/09 Crystal structure of PqsD, a key enzyme in Pseudomonas aeruginosa quinolone signal biosynthesis pathway Pseudomonas aeruginosa PAO1 1.8 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 586 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000962 (605 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_43261
Search term: pqsD

Human Homologs

References

No references are associated with this feature.