Pseudomonas aeruginosa LESB58, PALES_43271 (pqsC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_43271
Name
pqsC
Replicon chromosome
Genomic location 4765461 - 4766507 (- strand)

Cross-References

RefSeq YP_002441911
GI 218893042
Entrez 7180725

Product

Feature Type CDS
Coding Frame 1
Product Name
Homologous to beta-keto-acyl-acyl-carrier protein synthase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -7.49
Kyte-Doolittle Hydrophobicity Value -0.050
Molecular Weight (kDa) 38.2
Isoelectric Point (pI) 4.86

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6ET2 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 3) Pseudomonas aeruginosa PAO1 2.6 X-RAY DIFFRACTION 99.7
6ET1 TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 2) Pseudomonas aeruginosa PAO1 2.65 X-RAY DIFFRACTION 100.0
5DWZ TRANSFERASE 09/23/15 Structural and functional characterization of PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal Pseudomonas aeruginosa 2.04 X-RAY DIFFRACTION 99.7
6ESZ TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 1) Pseudomonas aeruginosa PAO1 1.84 X-RAY DIFFRACTION 100.0
6ET3 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4) Pseudomonas aeruginosa PAO1 2.25 X-RAY DIFFRACTION 99.7
6ET0 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1) Pseudomonas aeruginosa PAO1 1.53 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 539 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000961 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_43271
Search term: pqsC

Human Homologs

References

No references are associated with this feature.