Pseudomonas aeruginosa LESB58, PALES_49831 (mexD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_49831
Name
mexD
Replicon chromosome
Genomic location 5486213 - 5489344 (- strand)

Cross-References

RefSeq YP_002442564
GI 218893695
Entrez 7180475

Product

Feature Type CDS
Coding Frame 1
Product Name
Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexD
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -15.84
Kyte-Doolittle Hydrophobicity Value 0.403
Molecular Weight (kDa) 111.6
Isoelectric Point (pI) 4.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexD MexD is the multidrug inner membrane transporter of the MexCD-OprJ complex. [PMID:9449262, PMID:8878035] ARO:3000801 protein homolog model Strict 1842.8 95.43 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000417 (2093 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_49831
Search term: mexD

Human Homologs

References

No references are associated with this feature.