Pseudomonas aeruginosa LESB58, PALES_53061 (nadE)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest |
| Locus Tag |
PALES_53061
|
| Name |
nadE
|
| Replicon | chromosome |
| Genomic location | 5852038 - 5852865 (+ strand) |
Cross-References
| RefSeq | YP_002442884 |
| GI | 218894015 |
| Entrez | 7180687 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
NAD synthetase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -6.37 |
| Kyte-Doolittle Hydrophobicity Value | -0.193 |
| Molecular Weight (kDa) | 29.7 |
| Isoelectric Point (pI) | 5.38 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 4XFD | LIGASE | 12/26/14 | Crystal Structure of a NH(3)-dependent NAD(+) synthetase from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 1.55 | X-RAY DIFFRACTION | 100.0 |
| 5F23 | LIGASE | 12/01/15 | Crystal structure of NH(3)-dependent NAD(+) synthetase Pseudomonas aeruginosa in complex with NAD | Pseudomonas aeruginosa | 1.5 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 588 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004537 (530 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PALES_53061
Search term: nadE
Search term: NAD synthetase
|
Human Homologs
References
No references are associated with this feature.