Pseudomonas aeruginosa LESB58, PALES_56531 (hemD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_56531
Name
hemD
Replicon chromosome
Genomic location 6256670 - 6257425 (- strand)

Cross-References

RefSeq YP_002443231
GI 218894361
Entrez 7179316

Product

Feature Type CDS
Coding Frame 1
Product Name
uroporphyrinogen-III synthase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -6.64
Kyte-Doolittle Hydrophobicity Value -0.053
Molecular Weight (kDa) 27.2
Isoelectric Point (pI) 4.76

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4ES6 LYASE 04/22/12 Crystal structure of HemD (PA5259) from Pseudomonas aeruginosa (PAO1) at 2.22 A resolution Pseudomonas aeruginosa 2.22 X-RAY DIFFRACTION 100.0
6TH8 FLAVOPROTEIN 11/19/19 Reconstructing the Origins of the HemD-like fold Thermus thermophilus NOT SOLUTION NMR 94.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 195 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004840 (518 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_56531
Search term: hemD

Human Homologs

References

No references are associated with this feature.