Pseudomonas aeruginosa LESB58, PALES_59101
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest |
| Locus Tag |
PALES_59101
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 6543373 - 6544161 (+ strand) |
Cross-References
| RefSeq | YP_002443487 |
| GI | 218894617 |
| Entrez | 7179485 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
putative beta-lactamase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 5.90 |
| Kyte-Doolittle Hydrophobicity Value | -0.185 |
| Molecular Weight (kDa) | 29.1 |
| Isoelectric Point (pI) | 9.57 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| OXA-50 | OXA-50 is a beta-lactamase found in Pseudomonas aeruginosa. It confers decreased susceptibility to ampicillin and ticarcillin and, interestingly, to moxalactam and meropenem in P. aeruginosa but not in E. coli. Also confers resistance to piperacillin-tazobactam and cephalotin. [PMID:15155197] | ARO:3001796 | protein homolog model | Perfect | 542.0 | 100.0 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 90 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG005052 (303 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PALES_59101
Search term: putative beta-lactamase
|
Human Homologs
References
No references are associated with this feature.