Pseudomonas aeruginosa 2192, PA2G_03587

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_03587
Name
Replicon	chromosome
Genomic location	3982035 - 3983243 (- strand)

Cross-References

RefSeq	ZP_04936143.1
GI	254242821
NCBI Locus Tag	PA2G_03587
UniProtKB Acc	A3LFN1
UniProtKB ID	A3LFN1_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	MFS transporter
Synonyms
Evidence for Translation
Charge (pH 7)	13.88
Kyte-Doolittle Hydrophobicity Value	0.962
Molecular Weight (kDa)	41.8
Isoelectric Point (pI)	9.67

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
bcr-1	Transmembrane protein which expels bicyclomycin from the cell, leading to bicyclomycin resistance. Identified in Pseudomonas aeruginosa strains responsible for outbreaks in Brazil, often appearing with blaSPM-1, another bicyclomycin resistance gene. [PMID:25085655, PMID:26093374]	ARO:3003801	protein homolog model		Perfect	758.1	100.0	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001563 (351 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_03587 Search term: MFS transporter

Human Homologs

References