Pseudomonas aeruginosa 2192, PA2G_04610

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_04610
Name
Replicon	chromosome
Genomic location	5132562 - 5133203 (+ strand)

Cross-References

RefSeq	ZP_04937105.1
GI	254243783
NCBI Locus Tag	PA2G_04610
UniProtKB Acc	A3LIE3
UniProtKB ID	A3LIE3_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	orotate phosphoribosyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-4.31
Kyte-Doolittle Hydrophobicity Value	0.069
Molecular Weight (kDa)	23.3
Isoelectric Point (pI)	5.12

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name	Source Accession	Source DB	Version	Target Accession	Target Description	Percent Identity	Alignment Length	E-Value
Orotic Acid	DB02262	DrugBank	5.1.4	P08870	Orotate phosphoribosyltransferase	69.0	213	3.5e-82
5-O-phosphono-alpha-D-ribofuranosyl diphosphate	DB01632	DrugBank	5.1.4	P08870	Orotate phosphoribosyltransferase	69.0	213	3.5e-82

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004900 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_04610 Search term: orotate phosphoribosyltransferase

Human Homologs

References