Pseudomonas aeruginosa 2192, PA2G_04618

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_04618
Name
Replicon	chromosome
Genomic location	5139906 - 5140811 (- strand)

Cross-References

RefSeq	ZP_04937113.1
GI	254243791
NCBI Locus Tag	PA2G_04618
UniProtKB Acc	A3LIF1
UniProtKB ID	A3LIF1_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	acetylglutamate kinase
Synonyms
Evidence for Translation
Charge (pH 7)	-0.59
Kyte-Doolittle Hydrophobicity Value	0.184
Molecular Weight (kDa)	31.8
Isoelectric Point (pI)	6.81

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
2BUF	TRANSFERASE	06/12/05	Arginine Feed-Back Inhibitable Acetylglutamate Kinase	PSEUDOMONAS AERUGINOSA	2.95	X-RAY DIFFRACTION	100.0

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name	Source Accession	Source DB	Version	Target Accession	Target Description	Percent Identity	Alignment Length	E-Value
N-Acetyl-L-Glutamate	DB04075	DrugBank	5.1.4	Q9HTN2	Acetylglutamate kinase	100.0	301	1.8e-164

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004894 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_04618 Search term: acetylglutamate kinase

Human Homologs

References