Pseudomonas aeruginosa 2192, PA2G_05104

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 2192
GCF_000152545.1|latest
Locus Tag
PA2G_05104
Name
Replicon chromosome
Genomic location 5700696 - 5702045 (- strand)

Cross-References

RefSeq ZP_04937576.1
GI 254244254
NCBI Locus Tag PA2G_05104
UniProtKB Acc A3LJR4
UniProtKB ID A3LJR4_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
acetyl-CoA carboxylase biotin carboxylase subunit
Synonyms
Evidence for Translation
Charge (pH 7) -5.82
Kyte-Doolittle Hydrophobicity Value -0.184
Molecular Weight (kDa) 48.9
Isoelectric Point (pI) 6.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2C00 LIGASE 03/21/08 Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form PSEUDOMONAS AERUGINOSA 2.5 X-RAY DIFFRACTION 99.8
2VQD LIGASE 03/13/08 Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP PSEUDOMONAS AERUGINOSA 2.41 X-RAY DIFFRACTION 99.8

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004477 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2G_05104

Human Homologs

Ensembl 110, assembly GRCh38.p14
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value: 2.5e-119
Percent Identity: 47.3
Ensembl 110, assembly GRCh38.p14
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value: 2.5e-119
Percent Identity: 47.3
Ensembl 110, assembly GRCh38.p14
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value: 2.5e-119
Percent Identity: 47.3

References

No references are associated with this feature.